The Alchemist’s Approach to Metal Poisoning: Transforming the Metal Burden
نویسنده
چکیده
Metal poisoning is a global problem with humans being exposed to a wide range of metals in varying doses and varying time frames. Traditionally, treatment involves removal of the toxic source or chelation therapy. An intermediate approach is needed. This review outlines the argument for the use of essential metal supplementation as a strategy to induce metallothionein expression and displace the toxic metal from important biological systems, improving the metal burden of the patient. Specific recommendations are given for supplementation with calcium, zinc and vitamin E as a broad strategy to improve the status of those exposed to toxic metals.
منابع مشابه
Approach to Occupational Cases of Lead Poisoning
Introduction: Lead is a toxic metal that is found in the earth's crust and has been used by humans since 7000 years ago due to its density, malleability, high resistance and low melting point. The wide use of this metal in the industry, in addition to the exposure of workers, has led to widespread environmental pollution and public health problems in many parts of the world. Due to the widespre...
متن کاملClinical and Radiographic Findings of Heavy Metal Poisoning in Psittacine Birds
Objective- To evaluate the radiology application in diagnosis of heavy metal poisoning inbirds.Design- Descriptive study.Animals- In this article 4 suspected cases of heavy metal poisoning, including 3 African GreyParrots and a Sulfur Crested Cockatoo are described.Procedures- Presumptive diagnosis of heavy metal poisoning was made based on history andclinical signs including severe progressive...
متن کاملDesign, Synthesis and Antitubercular Evaluation of Novel Series of Pyrazinecarboxamide Metal Complexes
The interest in the synthesis of metallic complexes of different drugs to make them moreefficient in biological environment of the human body is seen for the last few decades. Widerange of metal complexes are already used in clinical practice which encourages additionalresearch for innovating new metal based drugs, such as metal-mediated antibiotics, antiparasitic,antiviral, antibacterial, and ...
متن کاملDesign, Synthesis and Antitubercular Evaluation of Novel Series of Pyrazinecarboxamide Metal Complexes
The interest in the synthesis of metallic complexes of different drugs to make them moreefficient in biological environment of the human body is seen for the last few decades. Widerange of metal complexes are already used in clinical practice which encourages additionalresearch for innovating new metal based drugs, such as metal-mediated antibiotics, antiparasitic,antiviral, antibacterial, and ...
متن کاملMatrix-enhanced secondary ion mass spectrometry: The Alchemist’s solution?
Because of the requirements of large molecule characterization and high-lateral resolution SIMS imaging, the possibility of improving molecular ion yields by the use of specific sample preparation procedures has recently generated a renewed interest in the static SIMS community. In comparison with polyatomic projectiles, however, signal enhancement by a matrix might appear to some as the alchem...
متن کامل